Determination of the Flow Parameters of a Scattering Liquid in a Microfluidic Blood Vessel Phantom Based on Laser Speckle Contrast Imaging

The use of laser speckle-contrast imaging (LSCI) in studies of cerebral vessels in vitro using a microfluidic phantom is discussed. An LSCI device is shown to be able to recover values from recorded speckle patterns in conditions of stepwise gradation of the flow of a scattering liquid. These studies yielded a regression curve for flow and recorded speckle-contrast imaging-based values calculated using a spatial algorithm; accuracy parameters of this curve are calculated.