Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance
Nature Neuroscience(2024)
Abstract
Zhao et al . report that brain vessels have a major role in clearing Alzheimer's disease–related toxin Aβ from brain and show that PICALM gene product and its variant associated with an increased risk for Alzheimer's disease inactivate an Aβ clearance system in blood vessels, leading to Aβ brain accumulation and cognitive impairment.
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