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Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

Zhen Zhao,Abhay P. Sagare,Qingyi Ma,Matthew R. Halliday,Pan Kong,Kassandra Kisler,Ethan A. Winkler,Anita Ramanathan,Takahisa Kanekiyo,Guojun Bu,Nelly Chuqui Owens,Sanket V. Rege,Gabriel Si,Ashim Ahuja,Donghui Zhu,Carol A. Miller,Julie A. Schneider,Manami Maeda,Takahiro Maeda,Tohru Sugawara,Justin K. Ichida,Berislav V. Zlokovic

Nature Neuroscience（2024）

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Abstract
Zhao et al . report that brain vessels have a major role in clearing Alzheimer's disease–related toxin Aβ from brain and show that PICALM gene product and its variant associated with an increased risk for Alzheimer's disease inactivate an Aβ clearance system in blood vessels, leading to Aβ brain accumulation and cognitive impairment.
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