The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates T H 17 differentiation

Dan Lu, Liang Liu, Xin Ji, Yanan Gao, Xi Chen, Yu Liu, Yang Liu,Xuyang Zhao, Yan Li,Yunqiao Li, Yan Jin, Yu Zhang,Michael A McNutt,Yuxin Yin

Nature Immunology(2015)

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Abstract
Little is known about the phosphatases involved in the control of TH17 cells. Yin and colleagues demonstrate that the phosphatase DUSP2 targets the transcription activator STAT3 to regulate the differentiation and function of TH17 cells.
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