Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

A. Marijke Keestra,Maria G. Winter,Josef J. Auburger,Simon P. Fräßle,Mariana N. Xavier,Sebastian E. Winter,Anita Kim,Victor Poon,Mariëtta M. Ravesloot,Julian F. T. Waldenmaier,Renée M. Tsolis,Richard A. Eigenheer,Andreas J. Bäumler

Nature（2013）

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摘要

Salmonella effector proteins trigger host innate immunity through the activation of small Rho GTPases, which, in turn, is sensed by the NOD1/2 signalling pathway.

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