Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer.

Garrett L Jensen,Niloufar Pourfarrokh,Marcus Volz,Linden L Morales,Kimberly Walker,Kendall P Hammonds, Moataz El-Ghamry, Lucas Wong,Parsa Hodjat, Eduardo Castro,Arundhati Rao,Sameer G Jhavar

Clinical and translational radiation oncology（2023）

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摘要

Significantly greater tumor regression following LCRT was seen in MGMTh LARC. Methylation status may help identify good candidates for close observation without surgery following LCRT.

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关键词

advanced rectal cancer,rectal cancer,chemoradiation,mgmt

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