m6A regulator-mediated methylation modification patterns and tumor immune microenvironment characterization in endometrial cancer

Endometrial cancer(EC)is the second most prevalent fe-male reproductive system tumor after cervical cancer and its incidence is rising globally.1 Recently,N6-methyl-adenosine(m6A)has emerged as an important regulator of a variety of physiological and pathological processes,especially in promoting EC progression.2,3 However,the potential roles of m6A modification in EC and its immune landscape remain unknown.