Prevalence and predicting factors of acute kidney injury due to methanol intoxication; a systematic review

Introduction: Methanol intoxication and subsequence acute kidney injury (AKI) can be dangerous and deadly in case of a missed or delayed diagnosis; therefore, identifying its prevalence and predictor factors is necessary.Objectives: This study was conducted to identify the prevalence and predictor factors of AKI in methyl alcohol-intoxicated patients. Methods and Materials: The search strategy was conducted with the standard keyword in the international database, including Web of Science, Scopus, PubMed /Medline, Embase, Cochrane, WorldCat, Dimension, OpenGrey, EBSCO, DOAJ, CINAHL, and Google scholar search engines. Studies that reported the prevalence of AKI due to methanol poisoning were included in this review study.Results: Results demonstrated that six studies from five countries, with a sample size of 816 methanol intoxication patients, were included in this study. Mean AKI prevalence in all reviewed studies was 28.18%; Gender male, hypertension, older age, anemia, alcohol overdose, sepsis, rhabdomyolysis, acute pancreatitis, and volume depletion were the reported AKI predictors in the reviewed studies. Conclusion: Identifying the AKI prevalence and its predictor factors in patients with methanol intoxication can help in their quick diagnosis, timely treatment, and reduce the subsequent complications.