Anti-proliferative effect of Annona extracts on breast cancer cells.

Maria-Luisa Veisaga,Mariam Ahumada,Stacy Soriano,Leonardo Acuna,Wei Zhang,Ivy Leung,Robert Barnum,Manuel A Barbieri

Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al（2023）

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摘要

Our study indicates that A. leaves (sub-fraction V) extract exhibits a selective anti-proliferative and proapoptotic effect on the metastatic MDA-MB-231 breast cancer cells through the involvement of PI3K/AKT/mTOR/S6K1 pathways.

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关键词

Annona montana,Cancer cell lines,Apoptosis,Anti-proliferative,Cell cycle,AKT,mTOR

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