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Identification of MRT-2359 a potent, selective and orally bioavailable GSPT1-directed molecular glue degrader (MGD) for the treatment of cancers with Myc-induced translational addiction

Gerald Gavory,Mahmoud Ghandi,Anne-Cecile d'Alessandro,Debora Bonenfant,Agustin Chicas,Frederic Delobel, Brad Demarco,Alexander Flohr,Christopher King,Anne-Laure Laine,Vittoria Massafra,Rajiv Narayan,Arnaud Osmont,Giorgio Ottaviani,Dave Peck,Sarah Pessa, Nooreen Rubin,Thomas Ryckmans,Martin Schillo,Ambika Singh,Simone Tortoioli, Dominico Vigi, Vladislav Zarayskiy,John Castle,Filip Janku,Owen Wallace,Silvia Buonamici,Bernhard Fasching

CANCER RESEARCH（2022）

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