Caged Colloids

Colloidal microcontainers, such as hollow capsules andcolloidosomes,have a range of applications, including drug delivery, energy storage,and artificial protocells. In this study, we present a versatile andscalable self-assembly approach for encapsulating cargo particleswithin well-defined porous membranes or cages. The encapsulation processinvolves camouflaging cargo within a liquid matrix that serves asa scaffold for satellite particles to form densely packed shells around.These satellites fuse to create self-standing cages, after which theliquid matrix is dissolved, trapping the cargo inside. By adjustingthe fusion protocol, we can control the porosity of the cages at variouslength scales. We demonstrate the potential of this technique by employingfunctional cargo to showcase transmembrane transport phenomena, suchas the delivery and active uptake of nanoparticles.