T-Lymphocyte Gene-Regulated CCL5 and Its Association with Extrahepatic Metastasis in Hepatocellular Carcinoma.

Guoping Dong,Fangying Fan, Yao He,Yanchun Luo,Jie Yu,Ping Liang

Journal of hepatocellular carcinoma（2023）

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摘要

Both CD4 and CD8 T lymphocyte subsets were independent risk factors for extrahepatic metastasis in HCC. Serum CCL5 levels could indicate the infiltration level of intra-tumoral CD8 T cells and the risk of extrahepatic metastasis in HCC patients, aiding in patient risk stratification for metastasis.

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关键词

cytokine CCL5, extrahepatic metastasis of hepatocellular carcinoma, peripheral lymphatic subset analysis, cytotoxic CD8+T cells

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