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Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq.

Mariana Bustamante Eduardo,Irene Keller, Nathalie Schuster,Stefan Aebi,Rolf Jaggi

Journal, genetic engineering & biotechnology（2023）

Cited 0|Views19
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Abstract
The present study provides new insights into the complex role of PR in ERα-positive/PR-positive breast cancer cells. Many of the genes affected by PR are part of central biological processes of tumorigenesis.
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Key words
Breast cancer,Estrogen receptor alpha,Progesterone receptor,Gene expression,RNA sequencing,CRISPR/Cas9
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