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Association between enlarged perivascular spaces and cerebrospinal fluid aquaporin-4 and tau levels: report from a memory clinic.

Luca Sacchi,Marina Arcaro,Tiziana Carandini,Anna Margherita Pietroboni,Giorgio Giulio Fumagalli,Chiara Fenoglio,Maria Serpente,Federica Sorrentino,Caterina Visconte, Manuela Pintus,Giorgio Conte,Valeria Elisa Contarino,Elio Scarpini,Fabio Triulzi,Daniela Galimberti,Andrea Arighi

Frontiers in aging neuroscience（2023）

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摘要
We provide evidence that CSO-EPVS and CSF-AQP4 might be clinically meaningful biomarkers of glymphatic dysfunction and associated neurodegeneration.
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关键词
glymphatic system, aquaporin-4, cerebrospinal fluid, Alzheimer's disease, brain perivascular spaces
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