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In silico evidence of Remdesivir action in blood coagulation cascade modulation in COVID-19 treatment.

Luis Gustavo Pagliarin,Lucca Miketen de Oliveira,Valentina Nunes Fontoura Dos Anjos,Cristiano de Bem Torquato de Souza,Gabrielle Caroline Peiter,Cinthia Façanha Wendel,Anderson Dillmann Groto,Fabrício Freire de Melo,Kádima Nayara Teixeira

World journal of biological chemistry（2023）

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Abstract
Because of the significant affinity, Remdesivir possibly could act in the severe acute respiratory syndrome coronavirus 2 infection blockade by interacting with ACE2 and concomitantly act in the modulation of the coagulation cascade preventing the hypercoagulable state.
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blood coagulation cascade modulation,remdesivir action
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