Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells.
bioRxiv : the preprint server for biology（2023）
Abstract
Chimeric mice expressing STING only in non-hematopoietic cells develop systemic and lung directed autoimmunity which recapitulates what is seen in pediatric patients with SAVI disease.
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Key words
autoreactive lymphocytes,lung,cells,gain-of-function
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