Proteomics-based identification of proteins in tumor-derived exosomes as candidate biomarkers for colorectal cancer.

Ge-Yu-Jia Zhou,Dong-Yan Zhao,Teng-Fei Yin,Qian-Qian Wang,Yuan-Chen Zhou,Shu-Kun Yao

World journal of gastrointestinal oncology（2023）

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摘要

In our study, comprehensive proteomic profiles were obtained for CRC tissue exosomes. Six exosomal proteins, NHP2, OLFM4, TOP1, SAMP, TAGL and TRIM28, may be promising diagnostic markers and effective therapeutic targets for CRC, but further experimental investigation is needed.

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关键词

exosomes,colorectal cancer,candidate biomarkers,proteins,proteomics-based,tumor-derived

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