Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment.
International journal of nanomedicine（2023）
Abstract
These results demonstrate that combination therapy using P/A/B@NM reshapes CAFs-mediated tumor stroma and immunosuppressive microenvironment, which can enhance the infiltration of CD8 T cells, thereby reactivating anti-tumor immunity for non-responsive TNBC cases.
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Key words
potentiating tnbc immunotherapy,reprogramming immunosuppressive microenvironment,tumor stroma,co-delivery,cafs-mediated
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