Comparing modeling strategies combining changes in multiple serum tumor biomarkers for early prediction of immunotherapy non-response in non-small cell lung cancer.

Frederik A van Delft,Milou M F Schuurbiers,Mirte Muller,Sjaak A Burgers,Huub H van Rossum,Maarten J IJzerman,Michel M van den Heuvel,Hendrik Koffijberg

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine（2023）

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摘要

Non-response in NSCLC patients treated with ICIs can be predicted with a specificity >95% by combining multiple sequentially measured STMs in a prediction model. Clinical use is subject to further external validation.

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