P53 regulates CCAAT/Enhancer Binding Protein β gene expression.
Gene（2023）
摘要
Analysis of the effects of P53 on C/EBPβ expression revealed a novel mechanism by which P53 could antagonize the effects of C/EBPβ on its target gene expression. For the first time, P53 is shown to be a repressor of C/EBPβ gene expression at both transcriptional and translational levels, with a differential effect in the magnitude of the effect on LAP vs. LIP isoforms.
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关键词
p53,ccaat/enhancer,gene expression,binding protein,ccaat/enhancer
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