Mitigative and anti-inflammatory effects of Trichostatin A against radiation induced gastrointestinal toxicity and gut microbiota alteration in mice.
International journal of radiation biology(2023)
摘要
These findings provide evidence that TSA inhibits inflammatory mediators, alleviates gut dysbiosis, and promotes structural restoration of the irradiated intestine. TSA, therefore, can be considered as a potential agent for mitigation of RIGI in humans.
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关键词
Trichostatin A, gastrointestinal injury, gut dysbiosis, inflammation, ionizing radiation, radiomitigator
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