从胃微生态探讨中医药防治胃癌前病变机制
Chinese Journal of Integrated Traditional and Western Medicine on Digestion（2021）
Abstract
慢性萎缩性胃炎(chronic atrophic gastritis,CAG)是常见的胃癌前疾病,以胃黏膜固有腺体萎缩为主要特征,可伴假幽门腺化生、肠上皮化生(intestinal metaplasia,IM)及异型增生等.Correa等[1]提出了肠型胃癌癌变模式,即正常胃黏膜→浅表性胃炎→CAG→IM→异型增生→肠型胃癌,其中IM和异型增生是主要的胃癌前病变(precan-cerous lesions of gastric cancer,PIGC),有效干预PLGC是阻断肠型胃癌发生的关键途径.目前,现代医学对该病治疗以根除Hp和对症治疗为主,尚无特异性治疗方法.中医药对PLGC的病因、病机和治疗等方面的认识较为成熟,并结合现代医学知识及检查手段,临床取得了良好的疗效[2].
MoreAI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined