Lenvatinib mitigates transarterial embolization-induced polarization of tumor-associated macrophages in a rat hepatocellular carcinoma model.

Eisuke Ueshima,Keitaro Sofue,Haruyuki Takaki,Yutaka Hirata,Hiroshi Kodama,Takuya Okada,Masato Yamaguchi,Koichiro Yamakado,Takamichi Murakami

Journal of vascular and interventional radiology : JVIR（2023）

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摘要

TAE induced M2 macrophage polarization. Lenvatinib administration with TAE could reprogram macrophage polarization, improving tumor immune microenvironment.

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关键词

BMDM,DEG,FFPE,FGF,FGFR,HCC,IVIS,TACE,TAE,TAM,TGF,TIME

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