儿童慢性乙型肝炎患者基于干扰素治疗策略的临床治愈之路

International Journal of Epidemiology and Infectious Disease(2020)

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Abstract
儿童慢性乙型肝炎(CHB)患者主要是通过IFN和核苷类似物进行抗病毒治疗,首选方案为IFN治疗。部分患者采取单一IFN或IFN联合或序贯核苷类似物抗病毒治疗,可以达到HBsAg清除即临床治愈的效果。目前面临的挑战是如何应用基于IFN的个体化抗病毒治疗策略使CHB患儿获得更多的临床治愈。
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Key words
Child,Chronic hepatitis B,Interferon,Nucleoside(acid) analogues,Clinical cure
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