Serotonin transporter-deficient mice display enhanced adipose tissue inflammation after chronic high-fat diet feeding.

Johannes Hoch, Niklas Burkhard, Shanshan Zhang,Marina Rieder,Timoteo Marchini,Vincent Geest,Krystin Krauel,Timm Zahn,Nicolas Schommer,Muataz Ali Hamad, Carolina Bauer,Nadine Gauchel,Daniela Stallmann,Claus Normann,Dennis Wolf, Rüdiger Eberhard Scharf,Daniel Duerschmied,Nancy Schanze

Frontiers in immunology（2023）

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摘要

Our observations suggest that SERT deficiency in mice is associated with inflammatory processes that manifest as increased adipose tissue inflammation upon chronic high-fat diet feeding due to enhanced leukocyte recruitment.

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关键词

adipose tissue inflammation,diet,transporter-deficient,high-fat

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