The methylation profile of IL4 , IL5 , IL10 , IFNG and FOXP3 associated with environmental exposures differed between Polish infants with the food allergy and/or atopic dermatitis and without the disease.

Marta Gorzkiewicz,Ewa Łoś-Rycharska,Julia Gawryjołek,Marcin Gołębiewski,Aneta Krogulska,Tomasz Grzybowski

Frontiers in immunology（2023）

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摘要

The methylation in allergic infants was lower than in the healthy ones. The methylation profile of , , , and associated with environmental exposures differed between the studied groups. The results offer insights into epigenetic regulation of immunological response in early childhood.

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关键词

DNA methylation, environmental exposure, allergy, IL4, IL5, IL10, IFNG, FOXP3

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