Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short-term aspirin use.

Amy Downing,Hayley Fenton,Claire Nickerson,Paul M Loadman,Elizabeth A Williams,Colin J Rees,Louise C Brown,Eva J A Morris,Mark A Hull

Alimentary pharmacology & therapeutics（2023）

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摘要

Individuals who received aspirin in the seAFOod trial demonstrated increased colorectal polyp risk during post-trial surveillance. Rebound elevated neoplastic risk after short-term aspirin use has important implications for aspirin cessation driven by age-related bleeding risk. ISRCTN05926847.

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