Using staged tree models for health data: Investigating invasive fungal infections by aspergillus and other filamentous fungi

Maria Teresa Filigheddu,Manuele Leonelli,Gherardo Varando, Miguel angel Gomez-Bermejo,Sofia Ventura-Diaz,Luis Gorospe,Jesus Fortun

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL(2024)

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摘要
Machine learning models are increasingly used in the medical domain to study the association between risk factors and diseases to support practitioners in understanding health outcomes. In this paper, we showcase the use of machine-learned staged tree models for investigating complex asymmetric dependence structures in health data. Staged trees are a specific class of generative, probabilistic graphical models that formally model asymmetric conditional independence and non-regular sample spaces. An investigation of the risk factors in invasive fungal infections demonstrates the insights staged trees provide to support medical decision-making.
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关键词
Diagnostic criteria,Invasive aspergillosis,Machine learning,Probabilistic graphical models,Staged trees
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