Estimation of Interstitial Glucose from physical activity measures using Grammatical Evolution

People with diabetes need to have their glucose levels under control, and it is essential for them to be able to know or estimate their glucose levels at any time. Continuous glucose monitors are commonly used, which measure interstitial glucose, an approximation of blood glucose, by means of a small catheter. Although most devices are not very intrusive, they do present some discomfort, and it would be preferable if these glucose levels could be estimated non-invasively, for example, through other physiological measurements collected in a simple way. This abstract describes our research on the performance of different grammatical evolution techniques to obtain accurate estimations of actual subcutaneous glucose values from non-invasive physiological measures, steps, calories and heart rates obtained with commercial smartwatches.