AI-based AlphaFold2 significantly expands the structural space of the autophagy pathway.

Nidhi Malhotra, Shantanu Khatri,Ajit Kumar,Akanksha Arun,Purba Daripa,Saman Fatihi,Sureshkumar Venkadesan,Niyati Jain,Lipi Thukral

Autophagy（2023）

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摘要

AF2: AlphaFold2; AF2-Mult: AlphaFold2 multimer; ATG: autophagy-related; CTD: C-terminal domain; ECTD: extreme C-terminal domain; FR: flexible region; MD: molecular dynamics; NTD: N-terminal domain; pLDDT: predicted local distance difference test; UBL: ubiquitin-like.

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autophagy,alphafold2,ai-based

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