Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the SSBP1 promoter region.

The study delved further into elucidating the anti-cancer mechanism of SNG in the context of osteosarcoma. Notably, we unraveled the previously undisclosed apoptotic potential of SSBP1 in osteosarcoma cells. This finding holds substantial promise in advancing the development of novel anti-cancer drugs and the identification of therapeutic targets.