Contribution of endocrine therapy in oestrogen receptor-positive pT1a-b breast cancer: Results of a retrospective study

Gilles Houvenaeghel,Alexandre de Nonneville,Monique Cohen,Jean-Marc Classe,Fabien Reyal,Chafika Mazouni,Christelle Faure,Alejandra Martinez, Marie-Pierre Chauvet,Emile Daraï, Charles Coutant,Pierre-Emmanuel Colombo, Pierre Gimbergues,Anne-Sophie Azuar,Roman Rouzier,Christine Tunon de Lara,Patrice Crochet,Sandrine Rua,Anthony Gonçalves

European Journal of Cancer（2022）

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摘要

•No endocrine therapy (ET) was significantly associated with decreased disease-free survival in all patients (hazard ratio = 1.275).•No ET was significantly associated with decreased disease-free survival in grade 2–3 tumours (hazard ratio = 1.502).•ET omission was not associated with decreased survival in 3047 grade 1 tumours.•ET omission may be considered in some patients with subcentimetric oestrogen receptor-positive cancer.

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关键词

Breast neoplasms,Oestrogen receptors,Tamoxifen,Aromatase inhibitors,Multivariate analysis,Retrospective studies,Disease-free survival

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