CHCHD2 Thr61Ile Mutation Impairs F1F0-ATPase Assembly in in Vitro and in Vivo Models of Parkinson's Disease.

Xiang Chen,Yuwan Lin,Zhiling Zhang,Yuting Tang,Panghai Ye,Wei Dai,Wenlong Zhang,Hanqun Liu,Guoyou Peng,Shuxuan Huang,Jiewen Qiu,Wenyuan Guo,Xiaoqin Zhu,Zhuohua Wu,Yaoyun Kuang,Pingyi Xu,Miaomiao Zhou

NEURAL REGENERATION RESEARCH（2024）

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Key words

ATP synthase (F1F0-ATPase),coiled-coil helix coiled-coil helix domain containing 2,dopaminergic neuron,mitochondrial dysfunction,neurodegeneration,oligomycin sensitivity-conferring protein,Parkinson's disease,T61I mutation,tyrosine hydroxylase

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