[ Naoluo Xintong Decoction activates caspase-1/Gasdermin D pathway to promote angiogenesis of rat brain microvascular endothelial cells after oxygen glucose deprivation/reperfusion injury].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University（2023）
Abstract
NLXTD can improve the proliferation, migration, and tube- forming ability and promote angiogenesis of BMECs with OGD/R injury probably by inhibiting the caspase-1/Gasdermin D pathway in pyroptosis, alleviating cell injury, and upregulating the expressions of VEGF and VEGFR2.
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Key words
rat brain microvascular,angiogenesis,endothelial cells,naoluo xintong decoction,oxygen glucose deprivation/reperfusion
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