[Analysis of therapeutic mechanism of Liushen Wan against colitis-associated colorectal cancer based on network pharmacology and validation in mice].

X Zhang,Y Chen,Z Li, J Shang, Z Yuan, W Deng,Y Luo, N Han,P Yin,J Yin

Nan fang yi ke da xue xue bao = Journal of Southern Medical University（2023）

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摘要

LSW can inhibit CAC in mice possibly by regulating the expression of TLR4 to reduce intestinal inflammation, inhibit colon tumor cell proliferation and promote their apoptosis.

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关键词

colorectal cancer,liushen wan,network pharmacology,therapeutic mechanism,colitis-associated

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