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Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

Kirit Singh,Kelly M. Hotchkiss,Ian F. Parney,John De Groot,Solmaz Sahebjam,Nader Sanai,Michael Platten,Evanthia Galanis,Michael Lim,Patrick Y. Wen,Giuseppe Minniti,Howard Colman,Timothy F. Cloughesy,Minesh P. Mehta,Marjolein Geurts,Isabel Arrillaga-Romany,Annick Desjardins,Kirk Tanner,Susan Short,David Arons,Elizabeth Duke,Wolfgang Wick,Stephen J. Bagley,David M. Ashley,Priya Kumthekar,Roel Verhaak,Anthony J. Chalmers,Anoop P. Patel,Colin Watts,Peter E. Fecci,Tracy T. Batchelor,Michael Weller,Michael A. Vogelbaum,Matthias Preusser,Mitchel S. Berger,Mustafa Khasraw

Nature medicine（2023）

Cited 3|Views76
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Abstract
breakthrough in drug discovery for glioblastoma requires serial collection of tissue from the central nervous system via window of opportunity trials
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Key words
CNS cancer,Drug development,Policy,Biomedicine,general,Cancer Research,Metabolic Diseases,Infectious Diseases,Molecular Medicine,Neurosciences
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