Haplotypes of [-794(CATT) 5-8 /-173G>C] MIF gene polymorphisms and its soluble levels in cutaneous squamous cell carcinoma in western Mexican population.

Elizabeth Guevara-Gutiérrez,Marina Ramos-Súarez, Romina Angélica Villalobos-Ayala,Alberto Tlacuilo-Parra,José Francisco Muñoz-Valle, Victor Tarango-Martínez,Yeminia Valle,Jorge Ramón Padilla-Gutiérrez, José Manuel Rojas-Díaz,Emmanuel Valdés-Alvarado

Molecular genetics & genomic medicine（2023）

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摘要

Our findings suggest that 5C and 7G [-794(CATT) /-173G>C] MIF gene haplotypes are associated with susceptibility to SCC and that SCC patients present increased soluble levels of MIF.

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关键词

carcinoma, squamous cell,cytokines,haplotypes,macrophage migration inhibition factors,polymorphism, genetic

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