The neoadjuvant rectal score and a novel magnetic resonance imaging based neoadjuvant rectal score are stage independent predictors of long-term outcome in locally advanced rectal cancer.

Ross K McMahon,Sean M O'Cathail, Harikrishnan Nair, Colin W Steele,Jonathan J Platt, Michael Digby,Alec C McDonald,Paul G Horgan,Campbell S D Roxburgh

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland（2023）

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摘要

Neoadjuvant rectal score is validated as a surrogate end-point for long-term outcomes. mrNAR categories do not correlate with NAR but have stage-independent prognostic value. mrNAR may represent a novel surrogate end-point for future neoadjuvant treatments that focus on organ preservation.

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关键词

cCR, clinical complete response, LARC, MRI, mrNAR score, NAR score, neoadjuvant, organ preservation, pathological complete response, pCR, rectal cancer, surrogate end-point, watch and wait

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