Validation of metagenomic next-generation sequencing of bronchoalveolar lavage fluid for diagnosis of suspected pulmonary infections in patients with systemic autoimmune rheumatic diseases receiving immunosuppressant therapy.
Frontiers in medicine（2023）
摘要
The accuracy of mNGS was superior to that of the CMTs for the diagnosis of pulmonary infections in patients with SARDs treated with immunosuppressants. The rapid diagnosis by mNGS can ensure timely adjustment of treatment regimens to improve diagnosis and outcomes.
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关键词
metagenomic next-generation sequencing, systemic autoimmune rheumatic diseases, immunosuppressants, bronchoalveolar lavage fluid, pulmonary infection, antibiotics
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