The dosage of curcumin to alleviate movement symptoms in a 6-hydroxydopamine-induced Parkinson's disease rat model.

Xiaoyu Liu,Hao Zhang, Chuanfen Li, Zhibin Chen, Qian Gao,Muxuan Han,Feng Zhao, Dan Chen, Qiuyue Chen,Minghui Hu,Zifa Li,Sheng Wei,Xiwen Geng

Heliyon（2023）

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摘要

Curcumin alleviated 6-OHDA-induced movement symptoms in a PD rat model. Additionally, the effect of curcumin against PD indicated dose and duration dependent and the intervention of 160 mg/kg/d for 2 weeks showed optimally therapeutic effect.

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关键词

Curcumin,Parkinson's disease,Movement symptoms,Substantia nigra pars compacta,6-Hydroxydopamine,Behavioral tests

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