GATA-3 expression and its correlation with prognostic factors and survival in canine mammary tumors.

Frontiers in veterinary science(2023)

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摘要
Kaplan-Meier analysis of survival curves validated our previous findings that dogs with GATA-3 expression in ≥79.4% of cells had significantly higher survival rates ( < 0.001). The performance analysis showed that the expression of GATA-3 in ≥79.4% of cells effectively predicted survival or death in dogs with mammary tumors. Collectively, these results suggest that GATA-3 can be a relevant marker in the study of mammary tumor progression and has potential as a prognosis marker for predicting outcomes in canine mammary tumors.
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关键词
breast cancer, transcription factor, prognostic biomarker, tumor progression, survival, canine mammary tumors
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