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清热解毒中药通过NF-κB信号通路治疗肿瘤的研究进展

LI Xue, ZHANG Ying,HOU Wei,ZHENG Qi,QI Xin,PEI Yingxia,FAN Huiting, LIU Shuo,LIN Hongsheng

Global Traditional Chinese Medicine（2021）

Cited 1|Views18
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Abstract
热毒是肿瘤常见的病因之一,清热解毒中药在恶性肿瘤中医治疗中起着重要作用.研究表明,清热解毒中药可通过调节核转录因子-κB(nuclear factor kappa-B,NF-κB)信号转导通路对肿瘤起到治疗效果.本文现以NF-κB为靶标,按不同癌种分类,将清热解毒中药对肿瘤的抑制作用进行综述,包括:乳腺癌、非小细胞肺癌、结直肠癌、胰腺癌、肝癌和卵巢癌.以期为中医药开发具有靶向调控NF-κB的药物奠定基础,为中医药治疗肿瘤提供临床新思路.
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