Deep Learning for Segmentation of the Left Ventricle in Echocardiography

Two-dimensional echocardiography is the most widely used non-invasive imaging modality due to its fast acquisition time, low cost, and high temporal resolution. Accurate segmentation of the left ventricle in echocardiography is vital for ensuring the accuracy of subsequent diagnosis. Currently, numerous efforts have been made to automatize this task and various public datasets have been released in recent decades to further develop present research. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors, such as operation policies, machine protocols, treatment preference, etc. As a result, models trained on one dataset, regardless of volume, cannot be confidently utilized for the others. In this study, we investigated model robustness to dataset bias using two publicly available echocardiographic datasets. This work validates the efficacy of a supervised deep learning model for left ventricle segmentation and ejection fraction prediction, outside the dataset on which it was trained. The exposure of this model to unseen, but related samples without additional training maintained a good performance. However, a performance decrease from the original results can be observed, while the impact of quality is also noteworthy with lower quality data leading to decreased performance.