Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort.

Yik Weng Yew,Theresia Mina,Hong Kiat Ng,Benjamin Chih Chiang Lam,Elio Riboli,Eng Sing Lee,Jimmy Lee,Joanne Ngeow,Paul Elliott,Steven Tien Guan Thng,John C Chambers,Marie Loh

International journal of obesity (2005)（2023）

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摘要

We establish strong association of BMI with TEWL and skin pH, with MR results suggestive of a possible causal relationship of obesity with TEWL. It emphasizes the potential impact of obesity on skin barrier function and therefore opportunity for primary prevention.

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Genetics,Physiology,Risk factors,Medicine/Public Health,general,Public Health,Epidemiology,Internal Medicine,Metabolic Diseases,Health Promotion and Disease Prevention

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