Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias.
Clinical chemistry and laboratory medicine(2023)
摘要
In this study, we demonstrate robust analytical and diagnostic performance of this commercial progranulin kit for implementation in clinical laboratory practice. This easy-to-use test allows identification of potential mutation carriers, which may guide further evaluation of the patient. This assay might also be used to evaluate the effect of novel PGRN-targeting drugs and therapies.
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关键词
blood progranulin elisa,clinical validation
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