Adipocyte hypertrophy in mesenchymal stem cells from infants of mothers with obesity.

Madeline Rose Keleher,Shreya Shubhangi, Asya Brown,Allison M Duensing,Manoel E Lixandrão,Kathleen M Gavin,Harry A Smith,Katerina J Kechris,Ivana V Yang,Dana Dabelea,Kristen E Boyle

Obesity (Silver Spring, Md.)（2023）

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摘要

Ob-MSCs have an intrinsic propensity for adipocyte hypertrophy and reduced hyperplasia during adipogenesis in vitro, perhaps linked to greater Zfp423 content and changes in cell cycle pathway gene expression.

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关键词

mesenchymal stem cells,adipocyte hypertrophy,stem cells,obesity

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