Design Space Determination to Optimize DNA Complexation and Full Capsid Formation in Transient Raav Manufacturing.

Qiang Fu,Yong Suk Lee,Erica A. Green,Yongdan Wang, So Young Park,Ashli Polanco,Kelvin H. Lee,Michael Betenbaugh,David McNally,Seongkyu Yoon

Biotechnology and Bioengineering（2023）

引用 12|浏览8

关键词

Design of Experiments (DoE),Design Space (DS),Gene therapy manufacturing,Process Parameters (PPs),Product Quality Attributes (PQAs),Recombinant adeno-associated virus (rAAV)

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