Targeting the adenosine monophosphate-activated protein kinase signalling pathway by bempedoic acid attenuates Angiotensin II-induced cardiac remodelling in renovascular hypertension in rats.
Life sciences（2023）
Abstract
These findings indicate the cardioprotective and antihypertrophic activity of bempedoic acid, which are suggested to result from energy-independent AMPK downstream signalling activation.
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Key words
renovascular hypertension,bempedoic acid,angiotensin,monophosphate-activated,ii-induced
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