Causal association between serum total bilirubin and cholelithiasis: a bidirectional two-sample Mendelian randomization study.

Yang Sun,Shaojie Yang,Wanlin Dai,Zhuyuan Zheng,Xiaolin Zhang,Yuting Zheng,Jingnan Wang,Shiyuan Bi,Yunlong Duan,Shuodong Wu,Jing Kong

Frontiers in endocrinology（2023）

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摘要

Our MR study revealed that the serum total bilirubin was causally associated with the risk of cholelithiasis, and the genetic predisposition to cholelithiasis was causally associated with the increased serum total bilirubin levels.

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关键词

cholelithiasis,total bilirubin,mendelian randomization study,two-sample

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