Quantification of peanut allergens across recalled and nonrecalled lots of diagnostic peanut extracts

The detection, quantification, and standardization of peanut allergens across products that do contain or potentially might contain them are a key area of interest for patients and clinicians.1,2 In particular, the question of whether a product has a peanut allergen has implications for quality control when assuring that products either: (1) do not contain allergens or (2) contain allergens within a target range.3-5 Recently, the Food and Drug Administration (FDA) issued a recall in December 2022 on lots of peanut allergen skin test extracts that did not perform as expected because of a higher than normal rate of false-negative skin tests in truly allergic patients.