Sacubitril/valsartan effects on arrhythmias and left ventricular remodelling in heart failure: An observational study.

Mauro Acquaro,Laura Scelsi,Beatrice Pasotti, Alessandro Seganti,Marcello Spolverini,Alessandra Greco,Sandra Schirinzi,Annalisa Turco,Antonio Sanzo,Simone Savastano,Roberto Rordorf,Stefano Ghio

Vascular pharmacology（2023）

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摘要

Sacubitril/valsartan reduced the number of premature ventricular complexes and increased the percentage of biventricular pacing in a cohort of HFrEF patients already on optimal medical therapy. PVC reduction did not correlate with reverse left ventricular remodelling. Whether sacubitril/valsartan has any direct antiarrhythmic effects is an issue to be better explored in future studies.

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关键词

ARNi,Sacubitril/Valsartan,Heart failure with reduced ejection fraction,HFrEF,Arrhythmias,Premature ventricular complexes

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